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CIALIS (tadalafil) tablets Dosing

Publication date: 2018-04-24 04:51

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Do not store CIALIS or any other medicine in the bathroom or near a sink. Do not leave it on a window sill or in the car.

Cialis film-coated tablets - Summary of Product

There are no data with the use of Cialis in pregnant women to inform any drug-associated risks for adverse developmental outcomes. In animal reproduction studies, no adverse developmental effects were observed with oral administration of tadalafil to pregnant rats or mice during organogenesis at exposures up to 66 times the maximum recommended human dose (MRHD) of 75 mg/day ( see Data).

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A slightly higher incidence of ECG abnormalities, primarily sinus bradycardia, has been reported in patients treated with tadalafil once a day as compared with placebo. Most of these ECG abnormalities were not associated with adverse reactions.

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Patients with left ventricular outflow obstruction, (., aortic stenosis and idiopathic hypertrophic subaortic stenosis) can be sensitive to the action of vasodilators, including PDE5 inhibitors.

Data in patients over 65 years of age receiving tadalafil in clinical trials, either for the treatment of erectile dysfunction or the treatment of benign prostatic hyperplasia, are limited. In clinical trials with tadalafil taken on demand for the treatment of erectile dysfunction, diarrhoea was reported more frequently in patients over 65 years of age. In clinical trials with tadalafil 5 mg taken once a day for the treatment of benign prostatic hyperplasia, dizziness and diarrhoea were reported more frequently in patients over 75 years of age.

In Study J, the effect of Cialis 5 mg once daily on maximum urinary flow rate (Q max ) was evaluated as a secondary efficacy endpoint. Mean Q max increased from baseline in both the treatment and placebo groups (Cialis 5 mg: mL/sec, placebo: mL/sec) however, these changes were not significantly different between groups.

Four strengths of almond-shaped tablets are available in different sizes and different shades of yellow, and supplied in the following package sizes:

Read this important information before you start taking Cialis and each time you get a refill. There may be new information. You may also find it helpful to share this information with your partner. This information does not take the place of talking with your healthcare provider. You and your healthcare provider should talk about Cialis when you start taking it and at regular checkups. If you do not understand the information, or have questions, talk with your healthcare provider or pharmacist.

Tell all of your healthcare providers that you take Cialis. If you need emergency medical care for a heart problem, it will be important for your healthcare provider to know when you last took Cialis.

The mean volume of distribution is approximately 68 l, indicating that tadalafil is distributed into tissues. At concentrations, 99% of tadalafil in plasma is bound to proteins. Protein binding is not affected by impaired renal function.

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CIALIS (tadalafil) tablets Dosing Cialis tablets and alcohol

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